"Wine is a mocker, strong drink a brawler, and whoever is led astray by it is not wise." ESV
Have you ever been around drunk people? Have you ever been with a drunk friend? Have you ever been drunk? If so, this Proverb does not need a lot of explanation. You know what it means for alcohol to mock a person. Young's Literal Translation says “strong drink is noisy.” You know what that means.
Many Christians choose not to touch alcohol, for various possible reasons - this concept not least among them. Teetotalism is not something to mock - it is often a sign of wisdom. It is certainly a value-judgment. For some people, the rewards are not worth the apparent risks.
Many Christians, and indeed most people around the globe, do use alcohol. If you use alcohol – beware. Make sure it isn't taking you for a ride. Because alcohol, if it leads you astray, will mock you. It will mock you loudly, and often publicly. Heed the warning. It is certainly frank enough to understand: whoever lets alcohol lead the way is not wise.